Glucose metabolism and its signaling in cancer and immune regulation
林慧觀
Hui-Kuan Lin
林慧觀 Hui-Kuan Lin
Director of Prostate Cancer Center
Current Position
Department of Cancer Biology
Wake Forest University School of Medicine
Education
National Taiwan University, Taipei, Taiwan, Taiwan, BS, 1993, Pharmacy
National Taiwan University, Taipei, Taiwan, Taiwan, MS, 1995, Pharmacology
University of Rochester, Rochester, NY, PHD, 2002, Pathology (Cancer Biology)
Curriculum Vitae
Zhang, W., Wang, G., Xu, ZG., Tu, F., Dai, J., Chang, Y., Chen, Y., Lu, Y., Zeng, H., Cai, Z., Han, F., Xu, C., Jin, G., Sun, L., Pan, BS., Lai, SW., Hsu, CC., Xu, J., Chen, Z., Li, HY., Seth P., Hu, J., Zhang, X., Li, H., Lin, HK. Lactate is a natural suppressor of RLR signaling by targeting MAVS. Cell. 2019 Jun 27;178(1):176-189.e15. doi: 10.1016/j.cell.2019.05.003. Epub 2019 May 30.
Wang G, Long J, Gao Y, Zhang. W, HanF, XuC, SunL, YangSC, Lan J, HouZ, CaiZ, Jin G, Hsu CC, Wang YH, Hu J, Chen TY, Li H, Lee MG, Lin HK.SETDB1-mediated methylation of Akt promotes its K63-linked ubiquitination and activation leading to tumorigenesis. Nat. Cell Biol. 2019 Feb;21(2):214-225.
Chan CH, Morrow JK, Li CF, Gao Y, Jin G, Moten A, Stagg LJ, Ladbury JE, Cai Z, Xu D, Logothetis CJ, Hung MC, Zhang S, Lin HK. Pharmacological Inactivation of Skp2 SCF Ubiquitin Ligase Restricts Cancer Stem Cell Traits and Cancer Progression. Cell 154(3):556-68, 8/2013.
Chan CH, Li CF, Yang WL, Gao Y, Lee SW, Feng Z, Huang HY, Tsai KK, Flores LG, Shao Y, Hazle JD, Yu D, Wei W, Sarbassov D, Hung MC, Nakayama KI, Lin HK. The Skp2-SCF E3 Ligase Regulates Akt Ubiquitination, Glycolysis, Herceptin Sensitivity, and Tumorigenesis. Cell 149(5):1098-111, 5/2012.
Yang WL, Wang J, Chan CH, Lee SW, Campos AD, Lamothe B, Hur L, Grabiner BC, Lin X, Darnay BG, Lin HK. The E3 ligase TRAF6 regulates Akt ubiquitination and activation. Science 325(5944):1134-1138, 8/2009.
林琬琬
Wan-Wan Lin
12:00 - 14:00
午餐 壁報論文競賽
13:00 - 14:20
陳烱霖轉譯醫學講座特別演講致德堂
Communication between cancer cells and immune cells during tumor progression
楊慕華
Muh-Hwa Yang
楊慕華 Muh-Hwa Yang
Chair professor of Institute of Clinical Medicine, Yang Ming Chiao Tung University
Current Position
Institute of Clinical Medicine, National Yang Ming Chiao Tung University
Education
M.D., National Yang-Ming University
Ph.D., National Yang-Ming University
Resident and clinical fellow of Division of Hematology-Oncology, Taipei Veterans General Hospital
Curriculum Vitae
Chen HY, Hsieh, CH, Lin PH, Chen YT, Hsu DS, Tai SK, Chu PY, Yang MH*. Snail regulated microRNA-21 suppresses NLRP3 inflammasome activity to enhance cisplatin resistance. J Immunother Cancer 2022;10:e004832.
Ou DL, Chen CW, Hsu CL, Chung CH, Feng ZR, Lee BS, Cheng AL, Yang MH*, Hsu C*. Regorafenib enhances antitumor immunity via inhibition of p38 kinase/Creb1/Klf4 axis in tumor-associated macrophages. J Immunother Cancer 2021;9:e001657.
Liao TT, Lin CC, Jiang JK, Yang SH, Teng HW, Yang MH*. Harnessing stemness and PD-L1 expression by AT-rich interaction domain-containing protein 3 in colorectal cancer. Theranostics 2020;10:6095-6112.
Li CF, Chen JY, Ho YH, Hsu WH, Wu, LC, Lan HY, Hsu DS, Tai SK, Chang YC*, Yang MH*. Snail-induced claudin-11 prompts collective migration for tumor progression. Nat Cell Biol 2019;21:251-262.
Hwang WL*, Lan HY, Cheng WY, Huang SC, Yang MH*. Tumor stem-Like cells-derived exosomal RNAs prime neutrophils for facilitating tumorigenesis of colon cancer. J Hematol Oncol 2019;12:10.
鄭子豪
TH Cheng
14:30 - 15:00
Plenary Speaker I
Vapor-Phase Fabrication of Scaffolds for Cellular and Tissue Engineering Applications
陳賢燁
Hsien-Yeh Chen
陳賢燁 Hsien-Yeh Chen
Professor 教授
Current Position
Department of Chemical Engineering/National Taiwan University
Molecular Imaging Center/ National Taiwan University
Education
Ph.D.
Chemical Engineering
University of Michigan- Ann Arbor
Plenary Speaker II
Development and application of multifunctional microbubbles for unconventional ultrasound mediated drug delivery: transdermal and inner ear
廖愛禾
Ai-Ho Liao
廖愛禾 Ai-Ho Liao
Professor/Vice dean in NTUST R & D office 教授兼副研發長
Current Position
Graduate Institute of. Biomedical Engineering, National Taiwan University of Science and Technology
Education
Ph.D. Electrical Engineering, National Taiwan University, Taiwan
M.S. Biomedical Imaging and Radiological Science (molecular imaging and nuclear medicine), National Yang-Ming University, Taiwan
B.S. Biomedical Imaging and Radiological Science, National Yang-Ming University, Taiwan
Curriculum Vitae
1.Ai-Ho Liao, Chih-Hung Wang, Bo-Han Wang, Yi-Chun Lin, Ho-Chiao Chuang, Hao-Li Liu, and Cheng-Ping Shih. Combined use of microbubbles of various sizes and single-transducer dual-frequency ultrasound for safe and efficient inner ear drug delivery. Bioengineering & Translational Medicine, e10450, 2022. (SCI) IF: 10.684, 12/98. Q1 (ENGINEERING, BIOMEDICAL)
2.Ai-Ho Liao, Yu-Chen Chen, Chia-Yu Chen, Shun Cheng Chang, Ho-Chiao Chuang, Dao-Lung Lin, Chien-Ping Chiang, Chih-Hung Wang, Jehng-Kang Wang. Mechanisms of ultrasound-microbubble cavitation for inducing the permeability of human skin. Journal of Controlled Release, 349:388-400, 2022. (SCI) IF: 11.467, 12/279. Q1 (PHARMACOLOGY & PHARMACY).
3.Ai-Ho Liao, Cheng-Ping Shih*, Ming-Wei Li, Yi-Chun Lin, Ho-Chiao Chuang, Chih-Hung Wang*. “Development of a thermosensitive poloxamer 407-based microbubble gel for ultrasound-mediated inner ear drug delivery” Drug Delivery, 28(1):1256-1271, 2021. (SCI) IF:6.819, 34/279. Q1 (PHARMACOLOGY & PHARMACY)
4.Ai-Ho Liao*, Yu-Jhen Huang, Ho-Chiao Chuang, Chih-Hung Wang, Cheng-Ping Shih, and Chien-Ping Chiang*. “Minoxidil-coated lysozyme-shelled microbubbes combined with ultrasound for the enhancement of hair follicle growth: Efficacy in vitro and in vivo” Frontiers in Pharmacology, 12: 668754, 2021. (SCI) IF:5.988, 50/279. Q1 (PHARMACOLOGY & PHARMACY)
5.Ai-Ho Liao, Chih-Hung Wang, Ping-Yu Weng, Yi-Chun Lin, Hao Wang, Hang-Kang Chen, Hao-Li Liu, Ho-Chiao Chuang, Cheng-Ping Shih*. “Exposure to ultrasound-induced microbubble cavitation via a transcanal or transcranial approach facilitates inner ear drug delivery through the round window membrane” JCI Insight, 5(3), pii: 132880, 2020. (SCI) IF:9.484, 9/139. Q1 (MEDICINE, RESEARCH & EXPERIMENTAL)
楊邦宏
YANG,BANG-HONG
16:00 - 16:30
Plenary Speaker III
Biocompatible nanomedicine for theranostic imaging
蘇家豪
Chia-Hao Su
蘇家豪 Chia-Hao Su
Professor/教授
Current Position
Center for General Education, Chang Gung University, Taoyuan, Taiwan.
Department of Biomedical Imaging and Radiological Sciences, National Yang Ming Chiao Tung University, Taipei, Taiwan.
Education
• Ph. D. in Department of Chemistry, National Cheng Kung University, Tainan, Taiwan (09/1997 – 10/2003)
• B.S. in Department of Chemistry, National Cheng Kung University, Tainan, Taiwan (09/1993 – 06/1997)
Curriculum Vitae
1.Chen, Y. C.; Liu, Y. J.; Lee, C. L.; Pham, K. Y.; Manoharan, D.; Thangudu, S.; Su, C. H.*; Yeh, C. S.* "Engineering H2O2 and O2 self-supplying nanoreactor to conduct synergistic chemiexcited photodynamic and calcium-overloaded therapy in orthotopic hepatic tumors" Adv. Healthc. Mater. 2022, 2201613. (SCI, IF: 1092 Material science, Biomaterials 9/53) (Corresponding author)
2.Thangudu, S.; Yu, C. C.; Lee, C. L.; Liao, M. C.; Su, C. H.* "Magnetic, biocompatible FeCO3 nanoparticles for T2-weighted magnetic resonance imaging of in vivo lung tumors" J. NanoBiotechnol. 2022, 20:157, 1-13. (SCI, IF: 10.435 Biotechnology & Applied microbiology 8/159) (Corresponding author)
3.Wang, L. C.; Chang, L. C.; Su, G. L.; Chang, P. Y.; Hsu, H. F.; Lee, C. L.; Li, J. R.; Liao, M. C.; Thangudu, S.; Treekoon, J.; Yu, C. C.; Sheu, H. S.; Tu, T. Y.; Su, W. P.; Su, C. H.*; Yeh, C. S.* "Chemical Structure and Shape Enhance MR Imaging-Guided Xray Therapy Following Marginative Delivery" ACS Appl. Mater. Interfaces 2022, 14, 13056-13069. (SCI, IF: 9.229 Materials science, multidisciplinary 33/314) (Co-Corresponding author)
4.Chen, Z. Z.; Wang, L. C.; Manoharan, D.; Lee, C. L.; Wu, L. C.; Huang, W. T.; Huang, E. Y.; Su, C. H.*; Sheu, H. S.; Yeh, C. S. "Low dose of X-ray-excited long-lasting luminescent concave nanocubes in highly passive targeting deep-seated hepatic tumors" Adv. Mater. 2019, 31, 1905087. (SCI, IF: 30.849 Chemistry, physical 4/168) (Co-Corresponding author)
5.Su, C. H.; Li, W. P.; Tsao, L. C.; Wang, L. C.; Hsu, Y. P.; Wang, W. J.; Liao, M. C.; Lee, C. L.; Yeh, C. S. "Enhancing microcirculation on multitriggering manner facilitates angiogenesis and collagen deposition on wound healing by photoreleased NO from hemin-derivatized colloids" ACS Nano 2019, 13(4), 4290-4301. (SCI, IF: 15.881 Chemistry, physical 11/168) (first author)
曹勤和
Tsao CH
16:30 - 17:00
Plenary Speaker IV
Comprehensive Characterization of Bone & Joint Phenotypes
連韋雄
Wei Shiung Lian
連韋雄 Wei Shiung Lian
Associate Research Fellow/副研究員
Current Position
Core Laboratory for Phenomics and Diagnostics, Kaohsiung Chang Gung Memorial Hospital, Kaohsiung, Taiwan.
Education
1. Ph.D., Department of Animal Science and Technology, National Taiwan University, Taipei, Taiwan
2. Training, Assistant Research Fellow (2017-2021), Kaohsiung Chang Gung Memorial Hospital, Kaohsiung, Taiwan.
Curriculum Vitae
1.Lian WS, Wu RW, Ko JY, Chen YS, Wang SY, Yu CP, Jahr H, Wang FS. (2022, Jun). Histone H3K27 demethylase UTX compromises articular chondrocyte anabolism and aggravates osteoarthritic degeneration. Cell Death Dis., 13(6):538.
2.Lian WS, Wu RW, Chen YS, Ko JY, Wang SY, Jahr H, Wang FS. (2021, Aug). MicroRNA-29a Mitigates Osteoblast Senescence and Counteracts Bone Loss through Oxidation Resistance-1 Control of FoxO3 Methylation. Antioxidants (Basel)., 10(8):1248.
3.Wang FS, Kuo CW, Ko JY, Chen YS, Wang SY, Ke HJ, Kuo PC, Lee CH, Wu JC, Lu WB, Tai MH, Jahr H, Lian WS. (2020, Sep). Irisin Mitigates Oxidative Stress, Chondrocyte Dysfunction and Osteoarthritis Development through Regulating Mitochondrial Integrity and Autophagy. Antioxidants (Basel)., 9(9):810.
4.Lian WS, Ko JY, Chen YS, Ke HJ, Hsieh CK, Kuo CW, Wang SY, Huang BW, Tseng JG, Wang FS. (2019, Sep). MicroRNA-29a represses osteoclast formation and protects against osteoporosis by regulating PCAF-mediated RANKL and CXCL12. Cell Death Dis, 10(10):705.
5.Lian WS, Ko JY, Chen YS, Ke HJ, Wu SL, Kuo CW, Wang FS (2018, Sep). Chaperonin 60 sustains osteoblast autophagy and counteracts glucocorticoid aggravation of osteoporosis by chaperoning RPTOR. Cell Death Dis, 9(10):938.
張御展
CHANG,YU-CHAN
Time / 時間
Topic / 主題
Speaker / 講員
Moderator / 座長
Abstract / 摘要
08:30 - 10:10
口頭論文競賽
蘇家豪
Chia-Hao Su
柯建志
KE,JIAN-JHIH
10:20 - 11:00
學會特別演講
How to Cultivate Yourself as a Distinctive Biomedical Scientist
姚維仁
Wei-Jen Yao
姚維仁 Wei-Jen Yao
Chairman, CHIA-YI CHRISTIAN HOSPITAL
Current Position
Chairman, CHIA-YI CHRISTIAN HOSPITAL
Education
National Defense Medical College, Department of Medicine
Curriculum Vitae
1. Shih Hsien Lin1, Mei Hung Chi1, I. Hui Lee1, Kao Chin Chen1, Ying Chun Tai1, Wei Jen Yao1, Nan Tsing Chiu1, Dong Yu Yang1, Chun Yu Lin1, Po See Chen1, Yen Kuang Yang, 2021, A pilot study on the association between the blood oxygen level-dependent signal in the reward system and dopamine transporter availability in adults with attention deficit hyperactivity disorder. CNS Spectrums,
2. Dom-Gene Tu, Hsuan-Yu Chen1, Wei Jen Yao, 2021, Verification of the Efficacy of New Diagnostic Criteria for Retropharyngeal Nodes in a Cohort of Nasopharyngeal Carcinoma Patients. International Journal of Medical Sciences (Ivyspring International Publisher)-Vol. 18, Iss: 15, pp 3463-3469.
3. Ying Chun Tai1, Mei Hung Chi1, Ching Lin Chu1, Nan Tsing Chiu1, Wei Jen Yao1, Po See Chen1, Yen Kuang Yang, 2019, Availability of Striatal Dopamine Transporter in Healthy Individuals With and Without a Family History of ADHD, Journal of Attention Disorders (SAGE Publications)-Vol. 23, Iss: 7, pp 665-670
黃文盛
Wen-Sheng, Huang
11:00 - 11:40
學會特別演講
Investigation of neurodegenerative disorders: applications of PET neuroimaging
馬國興
Kuo-Hsing Ma
馬國興 Kuo-Hsing Ma
Director, Department of Research and Development, National Defense Medical Center/國防醫學院 研究發展室 主任
Current Position
Director, Department of Research and Development, National Defense Medical Center
Professor, Graduate Institute of Biology and Anatomy, National Defense Medical Center
Education
B.S., School of Pharmacy, National Defense Medical Center
M.S., Graduate Institute of Biology and Anatomy, National Defense Medical Center
Ph.D., Graduate Institute of Life Sciences, National Defense Medical Center
Curriculum Vitae
Lin LF, Jhao YT, Chiu CH, Sun LH, Chou TK, Shiue CY, Cheng CY*, Ma KH*. Bezafibrate Exerts Neuroprotective Effects in a Rat Model of Sporadic Alzheimer's Disease. Pharmaceuticals (Basel). 2022 Jan 18;15(2):109. doi: 10.3390/ph15020109.
Weng SJ, Chen CF, Huang YS, Chiu CH, Wu SC, Lin CY, Chueh SH, Cheng CY, Ma KH*. Olfactory ensheathing cells improve the survival of porcine neural xenografts in a Parkinsonian rat model. Xenotransplantation. 2020 Mar;27(2):e12569.
Huang KF#, Ma KH#, Jhap TY, Liu PS, Chueh SH. Ultraviolet B irradiation induced Nrf2 degradation occurs via activation of TRPV1 channels in human dermal fibroblasts. Free Radic Biol Med. 2019 Sep;141:220-232. #Co-first author
Jhao YT, Chiu CH, Chen CF, Chou TK, Lin YW, Ju YT, Wu SC, Yan RF, Shiue CY, Chueh SH, Halldin C, Cheng CY*, Ma KH*. The Effect of Sertoli Cells on Xenotransplantation and Allotransplantation of Ventral Mesencephalic Tissue in a Rat Model of Parkinson's Disease. Cells. 2019 Nov 11;8(11):1420.
Weng SJ, Li IH, Huang YS, Chueh SH, Chou TK, Huang SY, Shiue CY, Cheng CY, Ma KH*. KA-bridged transplantation of mesencephalic tissue and olfactory ensheathing cells in a Parkinsonian rat model. J Tissue Eng Regen Med.2017 Jul;11(7):2024-2033.